Session Time: 12:30pm-2:00pm
Location: Research Hub - Kiosk 6
Disclosures: Reza Ehsanian, MD, PhD: Nothing to disclose
Objective: To determine the prevalence of vitamin B1 deficiency in the stroke population admitted to acute inpatient rehabilitation.
Design: Retrospective case series.
Setting: Acute inpatient rehabilitation.
Participants: 119 stroke patients admitted to stroke service from January 1, 2018 to December 31, 2018.
Interventions: Not applicable
Main Outcome Measures: Plasma vitamin B1 level.
Results: There were 17 patients with low vitamin B1 with a range of 2-3 nmol/L, 95% CI of median actual confidence level of 95.10% lower confidence limit (LCL) 2, upper confidence limit (UCL) 3, mean 2.29 (SD .47, SE 0.11), coefficient of variation 20.47%, Skewness .994, Kurtosis -1.17; 58 patients with low normal with a range of 4-9 nmol/L, 95% CI of median actual confidence level of 95.21% lower confidence limit (LCL) 6, upper confidence limit (UCL) 7, mean 6.41 (SD 1.58, SE 0.21), coefficient of variation 24.61%, Skewness .026, Kurtosis -0.96; 25 patients with normal with a range of 10-15 nmol/L, 95% CI of median actual confidence level of 95.67% lower confidence limit (LCL) 10, upper confidence limit (UCL) 12, mean 11.36 (SD 1.75, SE 0.351), coefficient of variation 15.43%, Skewness 1.06, Kurtosis -0.122; 19 patient with high vitamin B1 with a range of 16-43, 95% CI of median actual confidence level of 98.08% lower confidence limit (LCL) 18, upper confidence limit (UCL) 25, mean 22.74 (SD 7.16, SE 1.64), coefficient of variation 31.51%, Skewness 1.61, Kurtosis 2.28.
Conclusions: In this cohort of patients admitted to the stroke service at an acute rehabilitation facility there is evidence of thiamine deficiency. Given the role of thiamine deficiency in neurologic and cardiac function, further study of the role of thiamine optimization in the stroke population admitted to acute inpatient rehabilitation is warranted.
Level of Evidence: Level III
To cite this abstract in AMA style:Ehsanian R, Anderson S, Schneider B, Kennedy DJ, Mansourian V. Prevalence of Vitamin B1 Deficiency in the Stroke Population Admitted to Acute Inpatient Rehabilitation [abstract]. PM R. 2019; 11(S2)(suppl 2). https://pmrjabstracts.org/abstract/prevalence-of-vitamin-b1-deficiency-in-the-stroke-population-admitted-to-acute-inpatient-rehabilitation/. Accessed December 9, 2023.
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PM&R Meeting Abstracts - https://pmrjabstracts.org/abstract/prevalence-of-vitamin-b1-deficiency-in-the-stroke-population-admitted-to-acute-inpatient-rehabilitation/