Session Time: None. Available on demand.
Disclosures: Yingrong Zhu, MD:
Objective: Bladder Pain Syndrome/ Interstitial Cystitis (BPS/IC) is a complex debilitating condition characterized by bladder/pelvic pain and at least one urinary symptom. Objective is to determine the effectiveness of a neuromuscular protocol aimed at treating the central and peripheral neurogenic mechanisms involved in BPS/IC by addressing pelvic cross sensitization, neurogenic inflammation, and pelvic floor hypertonia.
Design: Retrospective studySetting : Outpatient pelvic rehabilitation practiceParticipants : 84 patients (54 female and 30 male) between ages of 22 to 86 diagnosed with BPS/IC with complaints of bladder symptoms
Interventions: Ultrasound-guided trigger point injections to the pelvic floor musculature, peripheral nerve blocks of the pudendal and posterior femoral cutaneous nerves, and pelvic floor physical therapy
Main Outcome Measures: Data was collected before treatment at patients’ first visit and 3 months after treatment at their 3-month follow up, using the 0 to 10 Visual Analogue Scale (VAS) to quantify pelvic pain and the Functional Pelvic Pain Scale (FPPS) to assess function. For VAS, patients were asked to rate their average pain intensity over the past 24 hours. Pelvic function on the FPPS encompasses eight categories: bladder, bowel, intercourse, walking, sleeping, working, running, and lifting. Patients rated each category from 0 to 4, with 0 for normal function, and 4 for severe debilitation.
Results: Pretreatment, mean VAS was 6.23 (Standard deviation [SD] 2.68); P < .05, 95% confidence interval (CI) 5.65 to 6.80. Posttreatment mean VAS was 3.90, (SD 2.63); P < .05, 95% CI 3.07 to 4.74. Mean FPPS before treatment was 11.98, (SD 6.28); P < .05, 95% CI 10.63 to 13.32. Posttreatment mean FPPS was 7.68, (SD 5.73); P < .05, 95% CI 6.45 to 8.90. Analysis of FPPS subcategories indicated highest statistical significance for categories of bladder, intercourse, and working.Conclusions: Analysis suggests the treatment was effective at ameliorating bladder pain and function including urinary urgency, frequency, and burning in BPS/IC patients.
Level of Evidence: Level III
To cite this abstract in AMA style:Zhu Y, Shrikhande AA, Patil SK, Tailor Y, Chudy C, Mamsaang MM. Effects of Treating the Underlying Neuromuscular Dysfunction in Bladder Pain Syndrome/ Interstitial Cystitis Patients [abstract]. PM R. 2021; 13(S1)(suppl 1). https://pmrjabstracts.org/abstract/effects-of-treating-the-underlying-neuromuscular-dysfunction-in-bladder-pain-syndrome-interstitial-cystitis-patients/. Accessed September 28, 2023.
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PM&R Meeting Abstracts - https://pmrjabstracts.org/abstract/effects-of-treating-the-underlying-neuromuscular-dysfunction-in-bladder-pain-syndrome-interstitial-cystitis-patients/