Session Time: 10:00am-10:45am
Location: Research Hub - Live Theater
Disclosures: Tahsin Ashraf, DO: Nothing to disclose
Objective: Accessing the effect of repetitive transcranial magnetic stimulation on motor/cognitive function following acute ischemic strokes.
Design: Case-control study
Setting: Rehabilitation unit in tertiary hospital.
Participants: 10 patients with recent acute ischemic stroke admitted to acute rehabilitation.
Interventions: Subjects received rTMS stimulation to the left dorsolateral prefrontal cortex (DLPFC) for 5 consecutive weekdays. Treatment consisted of 120% magnetic field intensity relative to the MT at 10Hz, 10 pulse per second, with a stimulus duration of 4 seconds and intertrain interval of 26 seconds.
Main Outcome Measures: MOCA, Boston Naming test, Fugl-Meyer upper extremity, Becks Depression inventory, and Hamilton Rating Scale for Depression were completed prior to and after the intervention.
Results: On Hamilton Rating Scale, patients scored an average of 6.00. Post treatment, patients scored an average of 3.25 with a deviation 2.67 showing significant improvement (P= .007). On Beck’s Depression inventory, patients scored an average of 10.08 and post-treatment, patients scored an average of 6.58 with a deviation of 4.72 which shows a significant improvement (P= .009). On Fugl-Meyer, patients scored an average of 10.70. Post-treatment patients scored an average of 20.30 and an average deviation of 21.03 which shows improvement significantly from baseline (P= .03). On MOCA, patients scored an average of 19.76 and after treatment an average of 21.75 with a deviation of 4.88 demonstrating significant improvement (P= .009). On the Boston naming task, patients scored an average of 12.67 and after treatment they scored an average of 13.25 with a deviation of 2.63. T test analysis shows that there was no difference in patient’s naming ability after baseline (P= .131).
Conclusions: Improvement was seen in motor and cognitive areas following rTMS. rTMS is a feasible treatment for acute ischemic stroke resulting in hemiplegia that can be used in acute inpatient rehabilitation along with therapy; however further research is needed in this area including controls.
Level of Evidence: Level III
To cite this abstract in AMA style:Ashraf T, Zhang J, Echaide C, Yu G, He S. Assessing the Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) After Acute Ischemic Stroke: Case-Control Study [abstract]. PM R. 2019; 11(S2)(suppl 2). https://pmrjabstracts.org/abstract/assessing-the-effect-of-repetitive-transcranial-magnetic-stimulation-rtms-after-acute-ischemic-stroke-case-control-study/. Accessed September 28, 2023.
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