Session Information
Date: Friday, November 15, 2019
Session Title: Musculoskeletal and Sports Medicine Research Report
Session Time: 12:30pm-2:00pm
Location: Research Hub - Kiosk 8
Disclosures: Aqeel M. Alenazi, PT, MSc: Nothing to disclose
Objective: To examine the association between multisite (> 2 sites) osteoarthritis (OA) and physical and mental health-related quality of life (HRQoL) among people with or without OA.
Design: Cross-sectional.
Setting: This study used data from the Osteoarthritis Initiative (OAI).
Participants: Data at baseline from 4,559 participants with mean age=61.179.19 were included. Participants were grouped based on a number of sites of OA into 4 groups: no OA, single-site OA, two sites OA or multisite OA (> 2 sites OA). The presence of OA was self-reported by the participants based on a confirmed diagnosis by their physicians.
Interventions: Not Applicable.
Main Outcome Measures: HRQoL was measured by health survey short form-12 for physical and mental composite scales. Multiple linear regression analysis models were used. Age, gender, race, body mass index and comorbidity score were included as covariates.
Results: After controlling for the covariates, multisite OA was significantly associated with lower physical composite score for HRQoL (B = -7.69, standard error (SE) = 0.47, 95% confidence interval (CI) [-8.60, -6.78], P <.001) when compared to no OA. Two sites OA and single site OA were also significantly associated with lower physical composite score for HRQoL when compared to no OA (B = -4.55, SE = 0.38, 95% CI [-5.30, -3.81], P <.001 and B = -2.26, SE = 0.29, 95% CI [-2.84, -1.68], P <.001, respectively). Only multisite OA was significantly associated with lower mental composite score HRQoL (B = -1.34, SE = 0.46, 95% CI [-2.23, -.44], P =.003).
Conclusions: Multisite OA was associated with decreased physical and mental HRQoL when compared to no OA. Single site and two sites OA were associated with reduced physical HRQoL only. The existence of multisite OA affects HRQoL to a greater extent and hence clinicians should utilize OA rehabilitation programs that are more comprehensive compared to single site OA.
Level of Evidence: Level II
To cite this abstract in AMA style:
Alenazi AM, Alshehri MM, Alqahtani BA, Yahya A, Bindawas SM, Kluding PM. The Relationship Between Multisite Osteoarthritis and Health-related Quality of Life: Data from the Osteoarthritis Initiative [abstract]. PM R. 2019; 11(S2)(suppl 2). https://pmrjabstracts.org/abstract/the-relationship-between-multisite-osteoarthritis-and-health-related-quality-of-life-data-from-the-osteoarthritis-initiative/. Accessed May 22, 2025.« Back to AAPM&R Annual Assembly 2019
PM&R Meeting Abstracts - https://pmrjabstracts.org/abstract/the-relationship-between-multisite-osteoarthritis-and-health-related-quality-of-life-data-from-the-osteoarthritis-initiative/