Session Information
Session Title: AA 2021 Virtual Posters - Pain and Spine Medicine
Session Time: None. Available on demand.
Disclosures: Krupali Chokshi, MD: No financial relationships or conflicts of interest
Case Diagnosis: A 51 year old female presenting with COVID Long-Haul symptoms.
Case Description: A 51 year old female infected with COVID-19 in March presented with nausea, diarrhea, fatigue, headaches, body aches and fevers for 8 months. She was noted to have elevated antibody levels and D-dimers and completed Eliquis for 7 days. She was seen by PM&R for persistent migraine headaches. The patient was prescribed 1-1 CBD: THC ratio and Sublingual 1-1 ratio for day time use and high dose Indica low dose CBD night time pill form and reported improvement in her migraine symptoms.
Setting: Outpatient Pain ClinicAssessment/
Results: This case highlights the effectiveness of CBD in patients with persistent symptoms long after a COVID infection.
Discussion: COVID-19 has resulted in devastating global, social and economic consequences. Many patients report persistent symptoms of clouded mentation, insomnia, exercise intolerance, fatigue, tachycardia, night sweats, gastrointestinal upset and low grade fevers. Limited research is available for this phenomenon coined “Long-Haul COVID” by many in the community. Cannabinoids (CBD) have far ranging therapeutic benefits and are thought to play a role in reducing the immune response and modulating inflammation. CBD1 and CBD2 receptors, present in the central nervous system tissue, lungs and circulating immune cells, are targeted to maintain immune homeostasis.
Conclusion: Long haul COVID symptoms can have a tremendous impact on a patient’s physical and cognitive function severely impacting their quality of life. CBD serves as a promising potential therapeutic intervention with broad anti-inflammatory properties to reduce symptom severity. Its availability, favorable side effect profile and high tolerability make it a natural and safe choice to relieve the prolonged burden of disease. Further research is needed to understand the pathophysiology of COVID-long haul symptoms and the potential for CBD to be used in large clinical trials to alleviate global morbidity and mortality.
Level of Evidence: Level V
To cite this abstract in AMA style:
Chokshi K, Jajoo P. Jack All of Trades, Master of All: Cannabis for Management of COVID-19 Long Haul Sequelae. A Case Report [abstract]. PM R. 2021; 13(S1)(suppl 1). https://pmrjabstracts.org/abstract/jack-all-of-trades-master-of-all-cannabis-for-management-of-covid-19-long-haul-sequelae-a-case-report/. Accessed May 11, 2025.« Back to AAPM&R Annual Assembly 2021
PM&R Meeting Abstracts - https://pmrjabstracts.org/abstract/jack-all-of-trades-master-of-all-cannabis-for-management-of-covid-19-long-haul-sequelae-a-case-report/