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Identification of Patients in Prolonged Disorders of Consciousness (PDOC) Using the UK Functional Assessment Measure (UKFIM+FAM): A Predictive Sensitivity Analysis

Lynne Turner-Stokes, DM FRCP (Northwick Park Hospital and King's College London, London, England)

Meeting: AAPM&R Annual Assembly 2021

Categories: Neurological Rehabilitation (2021)

Session Information

Session Title: Research Spotlight: Neurological Rehabilitation

Session Time: None. Available on demand.

Disclosures: Lynne Turner-Stokes, DM FRCP: Ipsen PLC (Products/Services: No) (Honorarium, Speaker/Honoraria includes speakers bureau, symposia, and expert witness)Kings’s College London (Products/Services: No) (Employment)London NorthWest University Healthcare NHS Trust (Products/Services: Yes) (Employment)

Objective: The UK Functional Assessment Measure (UKFIM+FAM) is a 30-item scale of motor, cognitive, communicative and psychosocial function. The objective was to determine whether the total UKFIM+FAM score can be used as a proxy to identify patients in vegetative or minimally conscious states (VS/MCS) and, if so, with what cut-off points.

Design: Retrospective analysis of prospectively-collected consecutive clinical cohort data.Setting : A specialist inpatient rehabilitation unit in the UK.Participants : All patients presenting in a prolonged disorder of consciousness (PDOC) between 2007-2019 (n=256).

Interventions: A PDOC evaluation programme

Main Outcome Measures: Consciousness was evaluated using validated measures (eg the Coma Recovery Scale-Revised). The UKFIM+FAM was recorded in parallel by the clinical team on admission and discharge.

Results: Demographics: Males 63%; Mean(SD) Age 43.5(14) yrs; Time since onset 17(31) weeks; Aetiology: 41% Trauma, 33% Hypoxia, 21% Stroke, 5% Other. Median UKFIM+FAM admission score=30 (IQR 30-31) with 90% scores Conclusions: The UKFIM+FAM can provide an acceptable proxy for identifying patients in PDOC. Taken together, the results suggest that total UKFIM+FAM scores of =35) would respectively provide a reasonably robust separation of VS/MCS versus Consciousness for the purpose of future evaluations.

Level of Evidence: Level II

To cite this abstract in AMA style:

Turner-Stokes L. Identification of Patients in Prolonged Disorders of Consciousness (PDOC) Using the UK Functional Assessment Measure (UKFIM+FAM): A Predictive Sensitivity Analysis [abstract]. PM R. 2021; 13(S1)(suppl 1). https://pmrjabstracts.org/abstract/identification-of-patients-in-prolonged-disorders-of-consciousness-pdoc-using-the-uk-functional-assessment-measure-ukfimfam-a-predictive-sensitivity-analysis/. Accessed May 20, 2025.
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