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Cranberry Supplementation for E.coli UTI Prophylaxis in Inpatient Stroke Rehabilitation: A Retrospective Analysis

Samir A. Khan, DO (Vanderbilt University Medical Center PM&R Program, Nashville, Tennessee); Vartgez Mansourian, MD; Nicholas Abramson, MD; Austin Sturdivant

Meeting: AAPM&R Annual Assembly 2022

Categories: General Rehabilitation (2022)

Session Information

Session Title: AA 2022 Posters - General Rehabilitation

Session Time: None. Available on demand.

Disclosures: Samir A. Khan, DO: No financial relationships or conflicts of interest

Objective: To test the hypotheses that oral cranberry supplementation (OCS) will decrease the incidence of Escherichia coli urinary tract infections (UTIs) in an inpatient stroke rehabilitation population, by acting as a prophylactic agent.

Design: Retrospective cohort study

Setting: Academic inpatient rehabilitation hospital, Stroke service

Participants: 176 consecutive patients over an 8-month period

Interventions: We started oral cranberry extract 300mg BID to all patients upon admission, except those patients on warfarin, with transplanted organs, or who declined.

Main Outcome Measures: Incidence of E.coli UTI when on OCS vs. not on OCS

Results: For patients on OCS (n=133) over an 8-month period, the incidence rate of E.coli UTI was 4.5% (6/133, 95% CI [1.7, 9.6]). During this timeframe, for patients not on OCS (n=43) the incidence rate of E.coli UTI was 2.3% (1/43, 95% CI [.06, 12.3]). This difference was not statistically significant (p=0.52).

Conclusions: OCS monotherapy did not significantly impact the incidence of E.coli UTI in an inpatient stroke rehabilitation population.

Level of Evidence: Level III

To cite this abstract in AMA style:

Khan SA, Mansourian V, Abramson N, Sturdivant A. Cranberry Supplementation for E.coli UTI Prophylaxis in Inpatient Stroke Rehabilitation: A Retrospective Analysis [abstract]. PM R. 2022; 14(S1)(suppl 1). https://pmrjabstracts.org/abstract/cranberry-supplementation-for-e-coli-uti-prophylaxis-in-inpatient-stroke-rehabilitation-a-retrospective-analysis/. Accessed May 18, 2025.
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