Session Information
Session Title: AA 2021 Virtual Posters - General Rehabilitation
Session Time: None. Available on demand.
Disclosures: Ali A. Weinstein, PhD: No financial relationships or conflicts of interest
Objective: To determine if patients with both type 2 diabetes (T2DM) and NAFLD have a different level of physical activity than those with NAFLD alone or healthy controls. In addition, to assess the relationship between their physical activity and the fine motor speed domain of a cognitive performance measure.
Design: Adult subjects were prospectively enrolled in a case-control study. Individuals with excess alcohol consumption or viral liver disease were excluded. NAFLD was diagnosed by sonographic assessment for evidence of hepatic steatosis by a radiologist. T2DM was defined as having a diagnosis of T2DM or having a glycated hemoglobin A1C value of ≥6.5.Setting : Community hospitalParticipants : Of 90 subjects included, 31% (Nf28) had NAFLD (71% male, age: 50.3±11.8, BMI: 32.4±6.1), 37% (Nf33) had T2DM+NAFLD (58% male, age: 56.3±9.5, BMI: 24.5±3.0) and 32% (Nf29) had neither NAFLD or T2DM (healthy controls: 55% male, age: 49.9±14.0, BMI: 34.2±5.3).
Interventions: N/A
Main Outcome Measures: Each participant was assessed on physical activity (Human Activity Profile), and a cognitive performance battery that included subtests from the Delis-Kaplan Executive Function System (trail making test) and the Wechsler Adult Intelligence Scale, 4th Edition (symbol search and coding).
Results: Patients with T2DM+NAFLD were less physically active (Average Activity Score (AAS) on HAP; 74.4±14.2) than those with NAFLD (81.0±10.4; p=0.05) or healthy controls (85.3±10.9; p=0.002). The three groups did not show differences on their cognitive performance domains (motor speed and processing speed). On the other hand, significant correlation was found between AAS and motor speed only among those with NAFLD (r=.54, p=0.003).Conclusions: The correlation between motor speed and physical activity among NAFLD suggests the importance of physical activity in maintaining cognitive performance in these patients.
Level of Evidence: Level III
To cite this abstract in AMA style:
Weinstein AA, Gerber NL, Younossi Z, Austin P, Avila LD, Escheik C, Price JK, Golabi P, Ngo D. Association of Physical Activity and Fine Motor Speed in Patients with Non-alcoholic Fatty Liver Disease (NAFLD) [abstract]. PM R. 2021; 13(S1)(suppl 1). https://pmrjabstracts.org/abstract/association-of-physical-activity-and-fine-motor-speed-in-patients-with-non-alcoholic-fatty-liver-disease-nafld/. Accessed May 11, 2025.« Back to AAPM&R Annual Assembly 2021
PM&R Meeting Abstracts - https://pmrjabstracts.org/abstract/association-of-physical-activity-and-fine-motor-speed-in-patients-with-non-alcoholic-fatty-liver-disease-nafld/