Disclosures: Catherine Jameson, DO: Nothing to disclose

Objective: Platelet rich plasma (PRP) has become a main component of regenerative medicine and here we present an approach to treating chronic tibialis anterior (TA) tendon/muscle pain with PRP. Our goal is to determine the effectiveness of PRP in treating anterior ankle pain after failed traditional conventional therapeutic treatments.

Design: Retrospective Chart Review

Setting: Outpatient Interventional Pain Clinic

Participants: Ages 18 or greater, both genders, tibialis anterior tendon pain for > 6 months, failed conservative therapies with no long-term improvement, and had not undergone previous regenerative injections.

Interventions: Ultrasound-guided PRP tibialis anterior tendon injection

Main Outcome Measures: Numeric Rating Scale (NRS) pre and post injection Opioid Dosage Reduction

Results: The average pain score at baseline was 8±1.5 on NRS scale. The average percent change in pain between baseline and 8 weeks post treatment was 36±23.2% reduction or improvement. There was a significant reduction or improvement in pain at 8 weeks post PRP treatment when compared with baseline, P=.008, according to the self-report percent change in pain. The average opioid reduction between baseline and 8 weeks post treatment was 17±21.2%. Three of the patients who were on opioid pain medications did not change the dosage of opioids after 8 weeks PRP treatment. No significant change in opioid reduction after 8 weeks post PRP treatment was shown in this study when compared with baseline, P=.063.

Conclusions: Platelet-rich plasma (PRP) has become an increasingly popular novel approach for physicians to treat chronic musculoskeletal pain. Our study demonstrated that its use in chronic tibialis anterior pain showed that 8 weeks post PRP treatment significantly improved chronic tibialis anterior pain. In addition, there was a difference in opioid dosages between at baseline and 8 weeks post-PRP treatment. Although not statistically significant, the study suggested a tendency of lower opioid pain medication dosages after 8 weeks post-PRP treatment.

Level of Evidence: Level IV

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PM&R Meeting Abstracts - https://pmrjabstracts.org/abstract/application-of-platelet-rich-plasma-to-chronic-tibialis-anterior-pain-a-case-series-presentation/