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Risk of Addiction, Depression, Anxiety and Childhood Abuse in Chronic Pain Patients

Elliot B. Bodofsky, MD (Cooper Hospital University Medical Center, Camden, New Jersey); Michael Sabia; Jessica Heil

Meeting: AAPM&R Annual Assembly 2022

Categories: Pain and Spine Medicine (2022)

Session Information

Session Title: Research Hub - Live Theater Research Spotlight: Pain and Spine Medicine

Session Time: None. Available on demand.

Disclosures: Elliot B. Bodofsky, MD: No financial relationships or conflicts of interest

Background and/or Objectives: To determine the prevalence of risk factors for addiction, as well as incidence of anxiety, depression, and childhood trauma in chronic pain patients on long term opioid therapy.

Design: Observational Study

Setting: Physical Medicine and Rehabilitation and Anesthesia academic medical center pain services.

Participants: 110 chronic pain patients age 18+ on opioids for 6+ months in the Optimizing Pain Treatment in New Jersey (OPTIN) study.

Interventions: The Addiction Severity Index Test (ASI), a measure of risk for addiction and substance misuse, the Adverse Childhood Experience Index (ACE), measuring childhood trauma and abuse, the PHQ9, a depression index, and the GAD7, an anxiety index

Main Outcome Measures: Index scores were analyzed to determine incidence of pathology and correlation between indices

Results: A small majority (52%) of OPTIN participants had ACE scores of 3 or higher, as compared with 20% in the general population (p

Conclusions: Most chronic pain patients in the OPTIN study did not show a high risk for substance abuse. A very significant percentage reported childhood trauma or abuse, and a large minority had evidence of generalized anxiety disorder and/or major depression. Several psychosocial indices were highly correlated. Multiple psychosocial problems were common.

Level of Evidence: Level II

To cite this abstract in AMA style:

Bodofsky EB, Sabia M, Heil J. Risk of Addiction, Depression, Anxiety and Childhood Abuse in Chronic Pain Patients [abstract]. PM R. 2022; 14(S1)(suppl 1). https://pmrjabstracts.org/abstract/risk-of-addiction-depression-anxiety-and-childhood-abuse-in-chronic-pain-patients/. Accessed May 17, 2025.
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